Starting treatment
Let's take you through the steps you'll need to take to ease into your treatment with KERENDIA.
How do I get started on KERENDIA?
Routine lab tests are a vital part of treatment
- Before starting on KERENDIA and throughout your treatment journey, your doctor will order lab work that will check the potassium levels in your blood, and do an eGFR test to check your kidney function
- Once your doctor has your lab results, they may adjust your dose as needed
- Your doctor will continue to routinely monitor your serum potassium and work with you to adjust your dose, if needed
How should I take KERENDIA?
It’s important to take KERENDIA as prescribed
- KERENDIA is a once-daily oral tablet. You should swallow the tablet whole
- If you are unable to swallow a whole tablet, KERENDIA may be crushed and mixed with water or soft foods such as applesauce immediately prior to use and taken orally
- If you miss a dose of KERENDIA, take your prescribed dose as soon as you remember before the next scheduled dose. Do not take 2 doses on the same day to make up for a missed dose
- Take KERENDIA as prescribed and do not start or stop any medicine before talking with your doctor, including your diabetes and high blood pressure medications. Check with your doctor or pharmacist if you’re not sure
- Tell your healthcare provider about all the prescription and over-the-counter medicines you take, including: salt substitutes, vitamins, and herbal or potassium supplements. KERENDIA may affect the way other medications work, and other medications may affect how KERENDIA works. Do not start or stop any medicine before you talk with your healthcare provider. Avoid grapefruit or grapefruit juice as it may increase KERENDIA levels in the blood
What are the most common side effects of KERENDIA?
- Hyperkalemia (potassium in your blood that is higher than normal)
- Hypotension (blood pressure that is lower than normal)
- Hyponatremia (sodium level in your blood that is lower than normal)
If you experience any of these side effects, you should notify your doctor immediately. Your doctor may change your dose if needed.
Starting KERENDIA is a great first step—but staying on treatment is just as important
KERENDIA is proven to slow the progression of chronic kidney disease in adults with type 2 diabetes (CKD in T2D) that could lead to kidney failure, dialysis, or kidney transplant. That’s why it’s critical to continue taking KERENDIA just as your doctor prescribed.
CKD in T2D is a progressive disease, which means that it cannot be cured and the damage to your kidneys cannot be reversed. As CKD gets worse, it may lead to kidney failure, requiring either dialysis or kidney transplant.
CKD in T2D often has no symptoms until you reach the later stages of CKD.
Ask your doctor about the importance of staying on KERENDIA.
The KERENDIA Digital Companion helps KERENDIA patients manage their treatment by providing them with customized medication and appointment reminders, treatment and condition-related information, and more. Download the free Medisafe app from your app store and add KERENDIA to get started.
KERENDIA
Getting Started Guide
Your treatment journey with KERENDIA is about to begin. Learn how to get started on treatment.
We're here to help
For questions about KERENDIA, financial support for your KERENDIA prescription, or patient support programs, please call 1-888-KERENDIA (537-3634).
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What is KERENDIA?
KERENDIA is a prescription medicine used to treat chronic kidney disease in adults with type 2 diabetes to reduce the risk of:
- Worsening of kidney disease
- Kidney failure
- Death due to cardiovascular disease
- Heart attack
- Hospitalization for heart failure
Important Safety Information
Do not take KERENDIA if you:
- Have problems with your adrenal glands
- Take certain medications called CYP3A4 inhibitors. Ask your healthcare provider if you are not sure if you are taking any of these medications
Before you take KERENDIA, tell your healthcare provider about all your medical conditions, including if you:
- Have high potassium levels in your blood (hyperkalemia) or take medications that may increase potassium levels in your blood. KERENDIA can cause hyperkalemia. Your healthcare provider will check your potassium levels before and during treatment with KERENDIA
- Have severe liver problems
- Are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed. Avoid breastfeeding during treatment with KERENDIA and 1 day after treatment
Tell your healthcare provider about all the prescription and over-the-counter medicines you take, including: salt substitutes, vitamins, and herbal or potassium supplements.
- KERENDIA may affect the way other medications work, and other medications may affect how KERENDIA works. Do not start or stop any medicine before you talk with your healthcare provider. Avoid grapefruit or grapefruit juice as it may increase KERENDIA levels in the blood
The most common side effects of KERENDIA include:
- Hyperkalemia (potassium level in your blood that is higher than normal)
- Hypotension (blood pressure that is lower than normal)
- Hyponatremia (sodium level in your blood that is lower than normal)
Please see the Prescribing Information for KERENDIA.
You are encouraged to report side effects or quality complaints of products to the FDA by visiting www.fda.gov/medwatch or calling 1-800-FDA-1088. For Bayer products, you can report these directly to Bayer by clicking here.
© 2022 Bayer Pharmaceuticals, Inc. All rights reserved.
BAYER, the Bayer Cross, and KERENDIA are registered trademarks of Bayer.
Last updated 01/2023.
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