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For adults with chronic kidney disease in type 2 diabetes (CKD in T2D)

G is for Getting
Started with
KERENDIA

Taking KERENDIA is a big step toward managing your chronic kidney disease in type 2 diabetes (CKD in T2D). The following information and resources can help make it easier to get started.

Why your lab work is important

Lab work is a normal part of living with CKD in T2D. You will likely have certain tests done before you start KERENDIA and at regular intervals throughout your treatment journey. Your test results can help your doctor: 

  • Understand the status of your CKD and track its progression over time
  • Choose your starting dose of KERENDIA or adjust it down the road if needed

You may find it helpful to keep track of your test results in an app like Medisafe™, which is available to download on Apple or Google Play.  

Taking KERENDIA

Icon of a bottle with text RX indicating prescription medication

It’s important to take KERENDIA as prescribed.

An icon of a glass of water half full with one tablet

KERENDIA is a once-daily oral tablet. You should swallow the tablet whole. If you are unable to swallow a whole tablet, KERENDIA may be crushed and mixed with water or soft foods such as applesauce immediately prior to use and taken orally.

Icon of a monthly calendar with a clock

If you miss a dose of KERENDIA, take your prescribed dose as soon as you remember before the next scheduled dose. Do not take 2 doses on the same day to make up for a missed dose.

Icon of a prescription with a magnifying glass

Take KERENDIA as prescribed and do not start or stop any medicine before talking with your doctor, including your diabetes and high blood pressure medications. Check with your doctor or pharmacist if you’re not sure.

Icon of a doctor with stethoscope around neck

Tell your healthcare provider about all the prescription and over-the-counter medicines you take, including: salt substitutes, vitamins, and herbal or potassium supplements. KERENDIA may affect the way other medications work, and other medications may affect how KERENDIA works. Do not start or stop any medicine before you talk with your healthcare provider. Avoid grapefruit or grapefruit juice as it may increase KERENDIA levels in the blood.

Most common side effects of KERENDIA

Hyperkalemia

Potassium in your blood that is higher than normal

Hypotension

Blood pressure that is lower than normal

Hyponatremia

Sodium level in your blood that is lower than normal

If you experience any of these side effects, you should notify your doctor immediately. Your doctor may change your dose if needed. Read more frequently asked questions about KERENDIA.

Your Guide to Getting Started

We’ve gathered the information you need to help you start on KERENDIA.

View the Getting Started Guide

Savings & Support

You may be able to save on your prescription. Our Insurance Navigator can guide you to the financial support programs that are right for you.

Learn How to Save On KERENDIA

Sign Up for the KERENDIA Patient Support Program

Find support on your terms. Connect one-on-one with a personal mentor, download the Medisafe™ app to set up reminders and track lab work, and sign up for onboarding emails to help guide your first few months on KERENDIA.

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What is KERENDIA?

KERENDIA is a prescription medicine used to treat chronic kidney disease in adults with type 2 diabetes to reduce the risk of:

  • Worsening of kidney disease
  • Kidney failure
  • Death due to cardiovascular disease
  • Heart attack
  • Hospitalization for heart failure

Important Safety Information

Do not take KERENDIA if you:
  • Have problems with your adrenal glands
  • Take certain medications called CYP3A4 inhibitors. Ask your healthcare provider if you are not sure if you are taking any of these medications
Before you take KERENDIA, tell your healthcare provider about all your medical conditions, including if you:
  • Have high potassium levels in your blood (hyperkalemia) or take medications that may increase potassium levels in your blood. KERENDIA can cause hyperkalemia. Your healthcare provider will check your potassium levels before and during treatment with KERENDIA
  • Have severe liver problems
  • Are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed. Avoid breastfeeding during treatment with KERENDIA and 1 day after treatment
Tell your healthcare provider about all the prescription and over-the-counter medicines you take, including: salt substitutes, vitamins, and herbal or potassium supplements.
  • KERENDIA may affect the way other medications work, and other medications may affect how KERENDIA works. Do not start or stop any medicine before you talk with your healthcare provider. Avoid grapefruit or grapefruit juice as it may increase KERENDIA levels in the blood
The most common side effects of KERENDIA include:
  • Hyperkalemia (potassium level in your blood that is higher than normal)
  • Hypotension (blood pressure that is lower than normal)
  • Hyponatremia (sodium level in your blood that is lower than normal)

Please see the Prescribing Information for KERENDIA.

Important Safety Information

Do not take KERENDIA if you:
  • Have problems with your adrenal glands
  • Take certain medications called CYP3A4 inhibitors. Ask your healthcare provider if you are not sure if you are taking any of these medications
Before you take KERENDIA, tell your healthcare provider about all your medical conditions, including if you:
  • Have high potassium levels in your blood (hyperkalemia) or take medications that may increase potassium levels in your blood. KERENDIA can cause hyperkalemia. Your healthcare provider will check your potassium levels before and during treatment with KERENDIA
  • Have severe liver problems
  • Are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed. Avoid breastfeeding during treatment with KERENDIA and 1 day after treatment
Tell your healthcare provider about all the prescription and over-the-counter medicines you take, including: salt substitutes, vitamins, and herbal or potassium supplements.
  • KERENDIA may affect the way other medications work, and other medications may affect how KERENDIA works. Do not start or stop any medicine before you talk with your healthcare provider. Avoid grapefruit or grapefruit juice as it may increase KERENDIA levels in the blood
The most common side effects of KERENDIA include:
  • Hyperkalemia (potassium level in your blood that is higher than normal)
  • Hypotension (blood pressure that is lower than normal)
  • Hyponatremia (sodium level in your blood that is lower than normal)

Please see the Prescribing Information for KERENDIA.