APPROVED for adults with heart failure with an ejection fraction of 40% or more
See how KERENDIA may help

NOW APPROVED for adults with heart failure with an ejection fraction of 40% or more

See how KERENDIA may be able to help

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Helpful Info

NOW APPROVED for adults with heart failure with an ejection fraction of 40% or more

See how KERENDIA may be able to help

APPROVED for adults with heart failure with an ejection fraction of 40% or more See how KERENDIA may help

For adults with chronic kidney disease in type 2 diabetes (CKD in T2D) 

Your Heart and Kidneys Are Connected

Your heart and kidneys are a team:

Heart and kidney icon
  • Your heart pumps blood through your body that gets filtered by your kidneys
  • Your kidneys also help control your blood pressure, which can affect your heart

That’s why CKD doesn’t just affect your kidneys—when one is under stress, the other can be affected, too.

CKD increases cardiovascular risk

When damage caused by CKD reduces the kidneys’ ability to do their job, more stress is put on the heart. CKD can increase your risk for cardiovascular events like heart attack. In fact, people with CKD in T2D are 3 times more likely to die from a cardiovascular event such as a heart attack than people who have T2D alone.

What is a cardiovascular event?

A cardiovascular (CV) event is a serious problem with your heart or blood vessels that can pose a risk to your health or life, and can include:

Icon of heart with lightening signs

1. Heart attack

Stethoscope icon with a medical cross

2. Hospitalization for heart failure

Icon of heart with a warning sign

3. Death due to CV disease

Your kidney numbers can also show CV risk

Your CV risk can be identified using the urine albumin-to-creatinine ratio (UACR):

Icon of urine specimen cup

A urine test that measures how much protein is in the urine

Alert warning icon with an exclamation mark in the centre.

Helps determine your risk of a CV event and if your kidneys are damaged

Heart and kidney icon

Consistent results of more than 30 mg/g indicate some level of CV risk and kidney damage

Cardiovascular risk icon

If protein shows up in your urine test, it may mean a higher risk of CV events. Starting treatment to slow the progression of your CKD can help reduce this risk.

KERENDIA helps your heart
and your kidneys

Learn About KERENDIA

Ask your healthcare provider
how KERENDIA can help with CKD in T2D

Download the Discussion Guide
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What is KERENDIA?

KERENDIA (finerenone) is a prescription medicine used to:

  • reduce the risk of worsening of kidney disease, kidney failure, death due to cardiovascular disease, heart attack, and hospitalization for heart failure in adults with chronic kidney disease (CKD) associated with type 2 diabetes (T2D) (10mg, 20mg tablets)
  • reduce the risk of death due to cardiovascular disease, hospitalization for heart failure, and urgent heart failure visits in adults with heart failure with left ventricular ejection fraction (HF LVEF) of ≥40%, when the heart may pump normally, but may not fill properly (10mg, 20mg, 40mg tablets)

Important Safety Information

Do not take KERENDIA if you:
  • Are allergic to any of the ingredients in KERENDIA
  • Take certain medications called CYP3A4 inhibitors. Ask your healthcare provider if you are not sure if you are taking any of these medications
  • Have problems with your adrenal glands
What are the possible side effects of KERENDIA?

KERENDIA may cause serious side effects, including:

  • High potassium levels in your blood (hyperkalemia). Your healthcare provider will check your potassium level before and during treatment with KERENDIA
  • Worsening of kidney function for patients with heart failure. Your healthcare provider will measure your kidney function before and during treatment with KERENDIA

The most common side effects of KERENDIA include hyperkalemia (potassium level in your blood that is higher than normal), hypotension (blood pressure that is lower than normal), and hyponatremia (sodium level in your blood that is lower than normal). Worsening of kidney function was also included in patients with heart failure.

Before you take KERENDIA, tell your healthcare provider about all your medical conditions, including if you:
  • Have high potassium levels in your blood (hyperkalemia) or take medications that may increase potassium levels in your blood
  • Have severe liver problems
  • Are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed. Avoid breastfeeding during treatment with KERENDIA and 1 day after treatment
Tell your healthcare provider about all the prescription and over-the-counter medicines you take, including salt substitutes, vitamins, and herbal or potassium supplements.
  • KERENDIA may affect the way other medications work, and other medications may affect how KERENDIA works. Do not start or stop any medicine before you talk with your healthcare provider. Avoid grapefruit or grapefruit juice as it may increase KERENDIA levels in the blood

Please see the full Prescribing Information for KERENDIA.

Important Safety Information

Do not take KERENDIA if you:
  • Are allergic to any of the ingredients in KERENDIA
  • Take certain medications called CYP3A4 inhibitors. Ask your healthcare provider if you are not sure if you are taking any of these medications
  • Have problems with your adrenal glands
What are the possible side effects of KERENDIA?

KERENDIA may cause serious side effects, including:

  • High potassium levels in your blood (hyperkalemia). Your healthcare provider will check your potassium level before and during treatment with KERENDIA
  • Worsening of kidney function for patients with heart failure. Your healthcare provider will measure your kidney function before and during treatment with KERENDIA

The most common side effects of KERENDIA include hyperkalemia (high potassium level in your blood), hyperkalemia (potassium level in your blood that is higher than normal), hypotension (blood pressure that is lower than normal), and hyponatremia (sodium level in your blood that is lower than normal). Worsening of kidney function was also included in patients with heart failure.

Before you take KERENDIA, tell your healthcare provider about all your medical conditions, including if you:
  • Have high potassium levels in your blood (hyperkalemia) or take medications that may increase potassium levels in your blood
  • Have severe liver problems
  • Are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed. Avoid breastfeeding during treatment with KERENDIA and 1 day after treatment
Tell your healthcare provider about all the prescription and over-the-counter medicines you take, including salt substitutes, vitamins, and herbal or potassium supplements.
  • KERENDIA may affect the way other medications work, and other medications may affect how KERENDIA works. Do not start or stop any medicine before you talk with your healthcare provider. Avoid grapefruit or grapefruit juice as it may increase KERENDIA levels in the blood

Please see the full Prescribing Information for KERENDIA.