Resources and Questions & Answers

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Downloadable resources

Here you’ll find helpful resources, including our doctor discussion guide and a patient brochure on chronic kidney disease in type 2 diabetes (CKD in T2D).

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KERENDIA Doctor Discussion Guide

Is KERENDIA right for you? Using this discussion guide with your doctor can help start a conversation.

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KERENDIA Patient
Resource Guide

KERENDIA
Patient Resource Guide

Turn to our Patient Resource Guide for important information to help you get started with treatment and to discover many resources available to you.

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Helpful support groups and websites
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Questions & Answers

Let's answer some questions you may have about KERENDIA. Remember, your doctor is always the best source to discuss any questions about your treatment and whether KERENDIA is right for you. For further assistance on any question that may not be below, please call 1-888-KERENDIA (537-3634).

    KERENDIA is a prescription medicine used to treat chronic kidney disease in adults with type 2 diabetes to reduce the risk of:

    • Worsening of kidney disease
    • Kidney failure
    • Death due to cardiovascular disease
    • Heart attack
    • Hospitalization for heart failure

    KERENDIA is a prescription medicine used to treat chronic kidney disease in adults with type 2 diabetes to reduce the risk of:

    • Worsening of kidney disease
    • Kidney failure
    • Death due to cardiovascular disease
    • Heart attack
    • Hospitalization for heart failure

    First, talk to your doctor about if KERENDIA is right for you.

    Before starting you on KERENDIA and throughout your treatment journey, your doctor will check the potassium levels in your blood and do an eGFR test to check your level of kidney function.

    After starting your treatment with KERENDIA, your doctor will work with you to schedule your lab work, including your potassium level, and adjust your dose, as needed.

    For tips on how to have a conversation with your doctor about KERENDIA treatment, and about CKD in T2D, download our Doctor Discussion Guide.

    It’s important to take KERENDIA as prescribed

    • KERENDIA is a once-daily oral tablet. You should swallow the tablet whole
    • If you are unable to swallow a whole tablet, KERENDIA may be crushed and mixed with water or soft foods such as applesauce immediately prior to use and taken orally
    • If you miss a dose of KERENDIA, take your prescribed dose as soon as you remember before the next scheduled dose. Do not take 2 doses on the same day to make up for a missed dose
    • Take KERENDIA as prescribed and do not start or stop any medicine before talking with your doctor, including your diabetes and high blood pressure medications. Check with your doctor or pharmacist if you’re not sure
    • Tell your healthcare provider about all the prescription and over-the-counter medicines you take, including: salt substitutes, vitamins, and herbal or potassium supplements. KERENDIA may affect the way other medications work, and other medications may affect how KERENDIA works. Do not start or stop any medicine before you talk with your healthcare provider. Avoid grapefruit or grapefruit juice as it may increase KERENDIA levels in the blood

    It’s important to take KERENDIA as prescribed

    • KERENDIA is a once-daily oral tablet. You should swallow the tablet whole
    • If you are unable to swallow a whole tablet, KERENDIA may be crushed and mixed with water or soft foods such as applesauce immediately prior to use and taken orally
    • If you miss a dose of KERENDIA, take your prescribed dose as soon as you remember before the next scheduled dose. Do not take 2 doses on the same day to make up for a missed dose
    • Take KERENDIA as prescribed and do not start or stop any medicine before talking with your doctor, including your diabetes and high blood pressure medications. Check with your doctor or pharmacist if you’re not sure
    • Tell your healthcare provider about all the prescription and over-the-counter medicines you take, including: salt substitutes, vitamins, and herbal or potassium supplements. KERENDIA may affect the way other medications work, and other medications may affect how KERENDIA works. Do not start or stop any medicine before you talk with your healthcare provider. Avoid grapefruit or grapefruit juice as it may increase KERENDIA levels in the blood

    If you miss a dose of KERENDIA, take your prescribed dose as soon as you remember before the next scheduled dose. Do not take 2 doses on the same day to make up for a missed dose.

    Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, salt substitutes, vitamins, and herbal or potassium supplements. KERENDIA may affect the way other medicines work, and other medicines may affect how KERENDIA works. Take KERENDIA as prescribed and do not start or stop any medicine before talking with your doctor, including your diabetes and high blood pressure medications.

    Do not take KERENDIA if you take certain medications called CYP3A4 inhibitors. Ask your healthcare provider if you are not sure if you are taking any of these.

    Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, salt substitutes, vitamins, and herbal or potassium supplements. KERENDIA may affect the way other medicines work, and other medicines may affect how KERENDIA works. Take KERENDIA as prescribed and do not start or stop any medicine before talking with your doctor, including your diabetes and high blood pressure medications.

    Do not take KERENDIA if you take certain medications called CYP3A4 inhibitors. Ask your healthcare provider if you are not sure if you are taking any of these.

    You were prescribed KERENDIA because your doctor determined it was appropriate to treat your CKD in type 2 diabetes.

    The disease is called chronic because the damage to your kidneys happens over a period of time and because it's a progressive disease, it means it gets worse over time. The sooner CKD is diagnosed, the more you can do to protect your kidneys from further damage.

    Talk to your doctor about how long you will need treatment with KERENDIA. Your doctor is the best person to ask about CKD in T2D, as well as KERENDIA treatment.

    If you have type 2 diabetes (T2D), inflammation and scarring can occur, causing damage to the kidneys. Over time, this may lead to chronic kidney disease (CKD), which involves a gradual loss of kidney function and can lead to permanent kidney damage. This damage to your kidneys may lead to kidney failure, dialysis, and kidney transplant.

    In addition, CKD in T2D can also lead to other serious health problems. For example, if you have CKD in T2D, you are 3 times more likely to die from a cardiovascular event such as a heart attack, than people who have T2D alone.

    The most common side effects of KERENDIA include:

    • Hyperkalemia (potassium level in your blood that’s higher than normal)
    • Hypotension (blood pressure that’s lower than normal)
    • Hyponatremia (sodium level in your blood that’s lower than normal)

    The most common side effects of KERENDIA include:

    • Hyperkalemia (potassium level in your blood that’s higher than normal)
    • Hypotension (blood pressure that’s lower than normal)
    • Hyponatremia (sodium level in your blood that’s lower than normal)

    If you experience any side effects, you should notify your doctor immediately. Your doctor may change your dose if needed.

    Call your healthcare provider for medical advice about side effects. Additionally, you may report side effects to FDA at 1-800-FDA-1088. Do not stop taking KERENDIA without speaking with your doctor.

    If you experience any side effects, you should notify your doctor immediately. Your doctor may change your dose if needed.

    Call your healthcare provider for medical advice about side effects. Additionally, you may report side effects to FDA at 1-800-FDA-1088. Do not stop taking KERENDIA without speaking with your doctor.

    Store KERENDIA at room temperature between 68°F to 77°F (20°C to 25°C).

    Yes–we’ve listed a number of them here.

    Yes–we’ve listed a number of them here.

    Eligible patients may pay as little as $10 per month for KERENDIA.* You can download and activate the KERENDIA Co-pay Savings Card at www.KERENDIAsavings.com. To learn more about the KERENDIA Savings Card and available financial support programs, visit our KERENDIA Financial Support page.

    Patients are eligible if they are commercially insured and may pay as little as $10 per month and save up to $3,000 per year. Patients who are enrolled in any type of government insurance or reimbursement programs are not eligible. Full terms and conditions apply. Visit KERENDIAsavings.com.

    Eligible patients may pay as little as $10 per month for KERENDIA.* You can download and activate the KERENDIA Co-pay Savings Card at www.KERENDIAsavings.com. To learn more about the KERENDIA Savings Card and available financial support programs, visit our KERENDIA Financial Support page.

    Patients are eligible if they are commercially insured and may pay as little as $10 per month and save up to $3,000 per year. Patients who are enrolled in any type of government insurance or reimbursement programs are not eligible. Full terms and conditions apply. Visit KERENDIAsavings.com.

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    We're here to help

    For questions about KERENDIA, financial support for your KERENDIA prescription, or patient support programs, please call 1-888-KERENDIA (537-3634).

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    Indication

    What is KERENDIA?

    KERENDIA is a prescription medicine used to treat chronic kidney disease in adults with type 2 diabetes to reduce the risk of:

    • Worsening of kidney disease
    • Kidney failure
    • Death due to cardiovascular disease
    • Heart attack
    • Hospitalization for heart failure

    Important Safety Information

    Do not take KERENDIA if you:
    • Have problems with your adrenal glands
    • Take certain medications called CYP3A4 inhibitors. Ask your healthcare provider if you are not sure if you are taking any of these medications
    Before you take KERENDIA, tell your healthcare provider about all your medical conditions, including if you:
    • Have high potassium levels in your blood (hyperkalemia) or take medications that may increase potassium levels in your blood. KERENDIA can cause hyperkalemia. Your healthcare provider will check your potassium levels before and during treatment with KERENDIA
    • Have severe liver problems
    • Are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed. Avoid breastfeeding during treatment with KERENDIA and 1 day after treatment
    Tell your healthcare provider about all the prescription and over-the-counter medicines you take, including: salt substitutes, vitamins, and herbal or potassium supplements.
    • KERENDIA may affect the way other medications work, and other medications may affect how KERENDIA works. Do not start or stop any medicine before you talk with your healthcare provider. Avoid grapefruit or grapefruit juice as it may increase KERENDIA levels in the blood
    The most common side effects of KERENDIA include:
    • Hyperkalemia (potassium level in your blood that is higher than normal)
    • Hypotension (blood pressure that is lower than normal)
    • Hyponatremia (sodium level in your blood that is lower than normal)

    Please see the Prescribing Information for KERENDIA.