Downloadable resources
Here you’ll find helpful resources, including our doctor discussion guide and a patient brochure featuring information about KERENDIA and how KERENDIA works.
KERENDIA Doctor Discussion Guide
Is KERENDIA right for you? Using this discussion guide with your doctor can help start a conversation about how to manage your CKD in T2D.
KERENDIA Brochure
Learn more about CKD in T2D and KERENDIA, including how it works and savings and support programs.
KERENDIA Getting
Started Guide
Your treatment journey with KERENDIA is about to begin. Learn how to get started on treatment.
Helpful support groups and websites
The National Kidney Foundation
Learn more about CKD in T2D and resources available to you.
Centers for Disease Control and Prevention CKD Risk CalculatorsCheck out these handy tools to calculate your risk of developing CKD, and the risk of progression to kidney failure if you already have CKD.
American Association of Kidney Patients
You’ll find lots of information, resources, and patient support here.
If you want more detailed information about CKD and how to manage it, you’ll find it at this website.
Know Diabetes By HeartLearn more about T2D and related resources available to you.
Questions & Answers
Let's answer some questions you may have about KERENDIA. Remember, your doctor is always the best source to discuss any questions about your treatment and whether KERENDIA is right for you. For further assistance on any question that may not be below, please call 1-888-KERENDIA (537-3634).
KERENDIA is a prescription medicine used to treat chronic kidney disease in adults with type 2 diabetes to reduce the risk of:
- Worsening of kidney disease
- Kidney failure
- Death due to cardiovascular disease
- Heart attack
- Hospitalization for heart failure
First, talk to your doctor about if KERENDIA is right for you.
Before starting you on KERENDIA and throughout your treatment journey, your doctor will check the potassium levels in your blood and do an eGFR test to check your level of kidney function.
After starting your treatment with KERENDIA, your doctor will work with you to schedule your lab work, including your potassium level, and adjust your dose, as needed.
For tips on how to have a conversation with your doctor about KERENDIA treatment, and about CKD in T2D, download our Doctor Discussion Guide.
It’s important to take KERENDIA as prescribed
- KERENDIA is a once-daily oral tablet. You should swallow the tablet whole
- If you are unable to swallow a whole tablet, KERENDIA may be crushed and mixed with water or soft foods such as applesauce immediately prior to use and taken orally
- If you miss a dose of KERENDIA, take your prescribed dose as soon as you remember before the next scheduled dose. Do not take 2 doses on the same day to make up for a missed dose
- Take KERENDIA as prescribed and do not start or stop any medicine before talking with your doctor, including your diabetes and high blood pressure medications. Check with your doctor or pharmacist if you’re not sure
- Tell your healthcare provider about all the prescription and over-the-counter medicines you take, including: salt substitutes, vitamins, and herbal or potassium supplements. KERENDIA may affect the way other medications work, and other medications may affect how KERENDIA works. Do not start or stop any medicine before you talk with your healthcare provider. Avoid grapefruit or grapefruit juice as it may increase KERENDIA levels in the blood
If you miss a dose of KERENDIA, take your prescribed dose as soon as you remember before the next scheduled dose. Do not take 2 doses on the same day to make up for a missed dose.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, salt substitutes, vitamins, and herbal or potassium supplements. KERENDIA may affect the way other medicines work, and other medicines may affect how KERENDIA works. Take KERENDIA as prescribed and do not start or stop any medicine before talking with your doctor, including your diabetes and high blood pressure medications.
Do not take KERENDIA if you take certain medications called CYP3A4 inhibitors. Ask your healthcare provider if you are not sure if you are taking any of these.
You were prescribed KERENDIA because your doctor determined it was appropriate to treat your CKD in type 2 diabetes.
The disease is called chronic because the damage to your kidneys happens over a period of time and because it's a progressive disease, it means it gets worse over time. The sooner CKD is diagnosed, the more you can do to help protect your kidneys from further damage.
Talk to your doctor about how long you will need treatment with KERENDIA. Your doctor is the best person to ask about CKD in T2D, as well as KERENDIA treatment.
If you have type 2 diabetes (T2D), inflammation and scarring can occur, causing damage to the kidneys. Over time, this may lead to chronic kidney disease (CKD), which involves a gradual loss of kidney function and can lead to permanent kidney damage. This damage to your kidneys may lead to kidney failure, dialysis, and kidney transplant.
In addition, CKD in T2D can also lead to other serious health problems. For example, if you have CKD in T2D, you are 3 times more likely to die from a cardiovascular event such as a heart attack, than people who have T2D alone.
The most common side effects of KERENDIA include:
- Hyperkalemia (potassium level in your blood that’s higher than normal)
- Hypotension (blood pressure that’s lower than normal)
- Hyponatremia (sodium level in your blood that’s lower than normal)
If you experience any side effects, you should notify your doctor immediately. Your doctor may change your dose if needed.
Call your healthcare provider for medical advice about side effects. Additionally, you may report side effects to FDA at 1-800-FDA-1088. Do not stop taking KERENDIA without speaking with your doctor.
Store KERENDIA at room temperature between 68°F to 77°F (20°C to 25°C).
Yes–we’ve listed a number of them here.
Eligible patients may pay as little as $0 per month for KERENDIA.* You can download and activate the KERENDIA Co-pay Savings Card at www.KERENDIAsavings.com. To learn more about the KERENDIA Savings Card and available financial support programs, visit our KERENDIA Financial Support page.
Patients are eligible if they are commercially insured and may pay as little as $0 per month and save up to $3000 per year. Patients who are enrolled in any type of government insurance or reimbursement programs are not eligible. Full terms and conditions apply, see KERENDIAsavings.com.
We're here to help
For questions about KERENDIA, financial support for your KERENDIA prescription, or patient support programs, please call 1-888-KERENDIA (537-3634).
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What is KERENDIA?
KERENDIA is a prescription medicine used to treat chronic kidney disease in adults with type 2 diabetes to reduce the risk of:
- Worsening of kidney disease
- Kidney failure
- Death due to cardiovascular disease
- Heart attack
- Hospitalization for heart failure
Important Safety Information
Do not take KERENDIA if you:
- Have problems with your adrenal glands
- Take certain medications called CYP3A4 inhibitors. Ask your healthcare provider if you are not sure if you are taking any of these medications
Before you take KERENDIA, tell your healthcare provider about all your medical conditions, including if you:
- Have high potassium levels in your blood (hyperkalemia) or take medications that may increase potassium levels in your blood. KERENDIA can cause hyperkalemia. Your healthcare provider will check your potassium levels before and during treatment with KERENDIA
- Have severe liver problems
- Are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed. Avoid breastfeeding during treatment with KERENDIA and 1 day after treatment
Tell your healthcare provider about all the prescription and over-the-counter medicines you take, including: salt substitutes, vitamins, and herbal or potassium supplements.
- KERENDIA may affect the way other medications work, and other medications may affect how KERENDIA works. Do not start or stop any medicine before you talk with your healthcare provider. Avoid grapefruit or grapefruit juice as it may increase KERENDIA levels in the blood
The most common side effects of KERENDIA include:
- Hyperkalemia (potassium level in your blood that is higher than normal)
- Hypotension (blood pressure that is lower than normal)
- Hyponatremia (sodium level in your blood that is lower than normal)
Please see the Prescribing Information for KERENDIA.
You are encouraged to report side effects or quality complaints of products to the FDA by visiting www.fda.gov/medwatch or calling 1-800-FDA-1088. For Bayer products, you can report these directly to Bayer by clicking here.
© 2022 Bayer Pharmaceuticals, Inc. All rights reserved.
BAYER, the Bayer Cross, and KERENDIA are registered trademarks of Bayer.
Last updated 01/2023.
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